Copper-catalyzed intermolecular C(sp3)–H bond functionalization towards the synthesis of tertiary carbamates† †Dedicated to Professor Iwao Ojima on his 70th birthday. ‡ ‡Electronic supplementary information (ESI) available: Experimental procedures, characterization data, and 1H and 13C NMR charts. See DOI: 10.1039/c5sc00238a

نویسندگان

  • Prasanna Kumara Chikkade
  • Yoichiro Kuninobu
  • Motomu Kanai
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Copper-catalyzed intermolecular C(sp3)-H bond functionalization towards the synthesis of tertiary carbamates.

We describe the development of an intermolecular unactivated C(sp3)-H bond functionalization towards the direct synthesis of tertiary carbamates. The transformation proceeded using a readily available, abundant first-row transition metal catalyst (copper), and isocyanates as the source of the amide moiety. This is a novel strategy for direct transformation of a variety of unactivated hydrocarbo...

متن کامل

Fluorine teams up with water to restore inhibitor activity to mutant BPTI† †Dedicated to Professor Iwao Ojima on the Occasion of his 70th Birthday. ‡ ‡Electronic supplementary information (ESI) available. See DOI: 10.1039/c4sc03227f Click here for additional data file.

Shijie Ye1, Bernhard Loll2, Allison Ann Berger1, Ulrike Mülow1, Claudia Alings2, Markus Christian Wahl2 and Beate Koksch1* Department of Biology, Chemistry, and Pharmacy, Freie Universität Berlin, 1. Institute of Chemistry and Biochemistry – Organic Chemistry, Takustrasse 3, 2. Institute of Chemistry and Biochemistry – Structural Biochemistry, Takustrasse 6, D-14195, Berlin, Germany *Correspond...

متن کامل

Tertiary amine synthesis via reductive coupling of amides with Grignard reagents† †Electronic supplementary information (ESI) available: Experimental procedures, spectroscopic data, copies of 1H and 13C NMR spectra and crystallographic data. CCDC 1552384. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7sc03613b Click here for additional data file. Click here for additional data file.

A new iridium catalyzed reductive coupling reaction of Grignard reagents and tertiary amides affording functionalised tertiary amine products via an efficient and technically-simple one-pot, two-stage experimental protocol, is reported. The reaction – which can be carried out on gram-scale using as little as 1 mol% Vaska's complex [IrCl(CO)(PPh3)2] and TMDS as the terminal reductant for the ini...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 6  شماره 

صفحات  -

تاریخ انتشار 2015